The nucleus acts as a ruler tailoring cell responses to spatial constraints
Abstract
The nucleus makes the rules Single cells continuously experience and react to mechanical challenges in three-dimensional tissues. Spatial constraints in dense tissues, physical activity, and injury all impose changes in cell shape. How cells can measure shape deformations to ensure correct tissue development and homeostasis remains largely unknown (see the Perspective by Shen and Niethammer). Working independently, Venturini et al. and Lomakin...
Paper Details
Title
The nucleus acts as a ruler tailoring cell responses to spatial constraints
Published Date
Oct 16, 2020
Journal
Volume
370
Issue
6514
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