TNAP as a therapeutic target for cardiovascular calcification: a discussion of its pleiotropic functions in the body
Abstract
Cardiovascular calcification (CVC) is associated with increased morbidity and mortality. It develops in several diseases and locations, such as in the tunica intima in atherosclerosis plaques, in the tunica media in type 2 diabetes and chronic kidney disease, and in aortic valves. In spite of the wide occurrence of CVC and its detrimental effects on cardiovascular diseases (CVD), no treatment is yet available. Most of CVC involve mechanisms...
Paper Details
Title
TNAP as a therapeutic target for cardiovascular calcification: a discussion of its pleiotropic functions in the body
Published Date
Oct 18, 2020
Journal
Volume
118
Issue
1
Pages
84 - 96
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