Chronic Lung Injury After Trimodality Therapy for Locally Advanced Non-Small Cell Lung Cancer

BackgroundTrimodality therapy is a treatment option for patients with locally advanced non-small cell lung cancer (LA-NSCLC). Thoracic radiation has both early (radiation pneumonitis) and late (chronic lung injury [CLI]) adverse effects on the lung. While CLI is expected to result in various problems in long-term survivors, these manifestations have not been precisely investigated.MethodsWe enrolled 112 LA-NSCLC patients who had received...