Inhibition of Renal Stellate Cell Activation Reduces Renal Fibrosis
Abstract
Interstitial fibrosis is a common feature of chronic kidney disease, and platelet-derived growth factor receptor-β (PDGFR-β)-positive mesenchymal cells are reportedly the major source of scar-producing myofibroblasts. We had previously demonstrated that albumin and its derivative R-III (a retinol-binding protein-albumin domain III fusion protein) inhibited the transdifferentiation/activation of hepatic stellate cells (HSCs) to myofibroblasts and...
Paper Details
Title
Inhibition of Renal Stellate Cell Activation Reduces Renal Fibrosis
Published Date
Oct 19, 2020
Journal
Volume
8
Issue
10
Pages
431 - 431
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