SMO mutations confer poor prognosis in malignant pleural mesothelioma

Volume: 9, Issue: 5, Pages: 1940 - 1951
Published: Oct 1, 2020
Abstract
Malignant pleural mesothelioma (MPM) is an aggressive tumor but approximately 12% of patients survive more than 3 years. The biological differences underlying better outcomes are not known. Several targeted agents and immunotherapy have been ineffective. Hedgehog (Hh) is one emerging pathway. We compared the biological profiles of patients with different survival, investigating the most frequently altered genes, including the Hh pathway.We...
Paper Details
Title
SMO mutations confer poor prognosis in malignant pleural mesothelioma
Published Date
Oct 1, 2020
Journal
Volume
9
Issue
5
Pages
1940 - 1951
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