Design and in vivo evaluation of a microparticulate depot formulation of buprenorphine for veterinary use
Abstract
Buprenorphine is a frequently used analgetic agent in veterinary medicine. A major drawback, however, is the short duration of action requiring several daily administrations. We therefore designed a poly-lactic-co-glycolic acid (PLGA) based microparticulate drug formulation for sustained parenteral drug release. Particles were designed to allow for a fast onset of action and a duration of the analgesic effect of at least two days in laboratory...
Paper Details
Title
Design and in vivo evaluation of a microparticulate depot formulation of buprenorphine for veterinary use
Published Date
Oct 14, 2020
Journal
Volume
10
Issue
1
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