Ru(bpy)₃²⁺‐Loaded Mesoporous Silica Nanoparticles as Electrochemiluminescent Probes of a Lateral Flow Immunosensor for Highly Sensitive and Quantitative Detection of Troponin I

The lateral flow immunosensor (LFI) is a widely used diagnostic tool for biomarker detection; however, its sensitivity is often insufficient for analyzing targets at low concentrations. Here, an electrochemiluminescent LFI (ECL‐LFI) is developed for highly sensitive detection of troponin I (TnI) using Ru(bpy) 3 2+ ‐loaded mesoporous silica nanoparticles (RMSNs). A large amount of Ru(bpy) 3 2+ is successfully loaded into the mesoporous silica...