MicroRNA determinants of neuroendocrine differentiation in metastatic castration-resistant prostate cancer.

Volume: 39, Issue: 49, Pages: 7209 - 7223
Published: Oct 9, 2020
Abstract
Therapy-induced neuroendocrine prostate cancer (NEPC), an extremely aggressive variant of castration-resistant prostate cancer (CRPC), is increasing in incidence with the widespread use of highly potent androgen receptor (AR)-pathway inhibitors (APIs) such as Enzalutamide (ENZ) and Abiraterone and arises via a reversible trans-differentiation process, referred to as neuroendocrine differentiation (NED). The molecular basis of NED is not...
Paper Details
Title
MicroRNA determinants of neuroendocrine differentiation in metastatic castration-resistant prostate cancer.
Published Date
Oct 9, 2020
Journal
Volume
39
Issue
49
Pages
7209 - 7223
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