Anti‐fibronectin Aptamers improve physiologic coagulum patterns and osteoblastic cells behavior

Background: Scaffolds functionalization with bioactive molecules provide specific proteins adsorption to biomaterial surface, attracting effector cells and, thus, potentiating new tissue formation. Aptamers are oligonucleotides that will bind with high affinity, specificity and stability to your target molecule and its association with 3D scaffolds has been proposed as a selective regenerative stimulator. Aim/Hypothesis: To observe how 3D...