From genoprotection to rejuvenation
Abstract
Aging results from aberrations in signaling mechanisms and decline in biologic activities and cellular functions. Anti-aging strategies include a number of dietary, genetic, and pharmacological interventions that converge on a core network of nutrient sensors including AMP-activated protein kinase (AMPK), mammalian target of rapamycin (mTOR), the insulin/insulin-like IIGF) growth factor signaling pathway (IIS), sirtuins, NFkB, and FOXO. Aging...
Paper Details
Title
From genoprotection to rejuvenation
Published Date
Jan 1, 2021
Journal
Volume
26
Issue
1
Pages
97 - 162
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Notes
History