Molecular Footprints of the Immune Assault on Pancreatic Beta Cells in Type 1 Diabetes
Abstract
Type 1 diabetes (T1D) is a chronic disease caused by the selective destruction of the insulin-producing pancreatic beta cells by infiltrating immune cells. We presently evaluated the transcriptomic signature observed in beta cells in early T1D and compared it with the signatures observed following in vitro exposure of human islets to inflammatory or metabolic stresses, with the aim of identifying “footprints” of the immune assault in the target...
Paper Details
Title
Molecular Footprints of the Immune Assault on Pancreatic Beta Cells in Type 1 Diabetes
Published Date
Sep 15, 2020
Journal
Volume
11
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