Myeloid-derived suppressor cells in gastroenteropancreatic neuroendocrine neoplasms

Expanded myeloid-derived suppressor cells (MDSCs) correlate with disseminated metastases and poor prognosis in various human cancers. However, the role of MDSCs in gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) is still unknown. We investigated the distribution of MDSCs and their clinical significance in patients with GEP-NENs. Peripheral blood mononuclear cells (PBMCs) and paraffin-embedded tumor tissues were acquired from patients...