BRAFV600E Overrides NOTCH Signaling in Thyroid Cancer
Abstract
Background: Several mechanisms likely cooperate with the mitogen-activated protein (MAP)-kinase pathway to promote cancer progression in the thyroid. One putative pathway is NOTCH signaling, which is implicated in several other malignancies. In thyroid cancer, data regarding the role of the NOTCH pathway are insufficient and even contradictory. Methods: A BRAFV600E-driven papillary thyroid carcinoma (PTC) mouse model was subjected to NOTCH...
Paper Details
Title
BRAFV600E Overrides NOTCH Signaling in Thyroid Cancer
Published Date
May 1, 2021
Journal
Volume
31
Issue
5
Pages
787 - 799
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