Efficient Synthesis of ω‐[ 18 F]Fluoroaliphatic Carboxylic Esters and Acids for Positron Emission Tomography

[ 18 F]Fluoroaliphatic carboxylic acids are important PET tracers that have demonstrated a considerable potential to address the fatty acid oxidation‐dependent processes in clinical patients. Herein, we report an efficient radiosynthetic approach to ω‐[ 18 F]fluoroaliphatic carboxylic esters and acids by nucleophilic radiofluorination of the readily available iodocarboxylic esters. Methyl 6‐[ 18 F]fluorohexanoate was further applied as a...