Therapeutic aspects of the Axl/Gas6 molecular system
Abstract
Axl receptor tyrosine kinase (RTK) and its ligand, growth arrest-specific protein 6 (Gas6), are involved in several biological functions and participate in the development and progression of a range of malignancies and autoimmune disorders. In this review, we present this molecular system from a drug discovery perspective, highlighting its therapeutic implications and challenges that need to be addressed. We provide an update on Axl/Gas6 axis...
Paper Details
Title
Therapeutic aspects of the Axl/Gas6 molecular system
Published Date
Dec 1, 2020
Journal
Volume
25
Issue
12
Pages
2130 - 2148
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