From Basic Science to Clinical Application of Polygenic Risk Scores: A Primer.

Volume: 78, Issue: 1, Pages: 101 - 109
Published: Jan 1, 2021
Abstract
Importance null Polygenic risk scores (PRS) are predictors of the genetic susceptibilities of individuals to diseases. All individuals have DNA risk variants for all common diseases, but genetic susceptibility differences between people reflect the cumulative burden of these. Polygenic risk scores for an individual are calculated as weighted counts of thousands of risk variants that they carry, where the risk variants and their weights have been...
Paper Details
Title
From Basic Science to Clinical Application of Polygenic Risk Scores: A Primer.
Published Date
Jan 1, 2021
Volume
78
Issue
1
Pages
101 - 109
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