Bone marrow mesenchymal stem cells-derived exosomal microRNA-193a reduces cisplatin resistance of non-small cell lung cancer cells via targeting LRRC1

Hongbo Wu; Xiaoqian Mu; Lei Liu; Huijuan Wu; Xiufeng Hu; Lijuan Chen; Jie Liu; Yu Mu; Fangfang Yuan; Wenjing Liu; Yanqiu Zhao

doi:https://doi.org/10.1038/s41419-020-02962-4

doi.org/10.1038/s41419-020-02962-4

Bone marrow mesenchymal stem cells-derived exosomal microRNA-193a reduces cisplatin resistance of non-small cell lung cancer cells via targeting LRRC1

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..., Yanqiu Zhao

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Cell Death and Disease

Volume: 11, Issue: 9

Published: Sep 25, 2020

Abstract

Exosomes are small endogenous membrane vesicles that can mediate cell communication by transferring genetic materials. Based on that, exosomes have always been discussed as a cargo carrier for microRNA (miRNA) transportation. Accumulating data have reported the inhibitory effects of microRNA-193a (miR-193a) on non-small cell lung cancer (NSCLC) cell progression. However, the mechanisms of miR-193a delivery to cancer cells and miR-193a in...

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Paper Details

Title

Bone marrow mesenchymal stem cells-derived exosomal microRNA-193a reduces cisplatin resistance of non-small cell lung cancer cells via targeting LRRC1

DOI

doi.org/10.1038/s41419-020-02962-4

Published Date

Sep 25, 2020

Journal

Cell Death and Disease

Volume

11

Issue

9

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