Lentinan improved the efficacy of vaccine against Trichinella spiralis in an NLRP3 dependent manner

Volume: 14, Issue: 9, Pages: e0008632 - e0008632
Published: Sep 25, 2020
Abstract
There is an urgent need for the development of new, improved vaccine adjuvants against T. spiralis infection. Polysaccharides are effective, safe, and biodegradable as adjuvant. In our study, we first observed the protective efficacy of lentinan as adjuvant against helminth T. spiralis infection. Recombinant T. spiralis Serpin (rTs-Serpin) immunoscreened from a cDNA library of T. spiralis, as a vaccine, protect host against Trichinella...
Paper Details
Title
Lentinan improved the efficacy of vaccine against Trichinella spiralis in an NLRP3 dependent manner
Published Date
Sep 25, 2020
Volume
14
Issue
9
Pages
e0008632 - e0008632
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