Comparative Analysis of Cardiac Effects of α1A-Adrenoreceptor Stimulation In Vivo and Ex Vivo in Newborn Rats
Volume: 169, Issue: 5, Pages: 605 - 608
Published: Sep 1, 2020
Abstract
The study examined the effects of α1A-adrenoceptor stimulation on chronotropic function of Langendorff-perfused isolated heart ex vivo and on cardiac chronotropy in vivo in 7-day-old rats. α1A-Adrenergic receptor agonist A-61603 reduced heart chronotropy only in the whole organism. No chronotropic effects of selective stimulation of α1A-adrenergic receptors on isolated hearts were observed in ex vivo experiments. These findings suggest that...
Paper Details
Title
Comparative Analysis of Cardiac Effects of α1A-Adrenoreceptor Stimulation In Vivo and Ex Vivo in Newborn Rats
Published Date
Sep 1, 2020
Volume
169
Issue
5
Pages
605 - 608
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