Mechanism of central hypopnoea induced by organic phosphorus poisoning
Abstract
Whether central apnoea or hypopnoea can be induced by organophosphorus poisoning remains unknown to date. By using the acute brainstem slice method and multi-electrode array system, we established a paraoxon (a typical acetylcholinesterase inhibitor) poisoning model to investigate the time-dependent changes in respiratory burst amplitudes of the pre-Bötzinger complex (respiratory rhythm generator). We then determined whether pralidoxime or...
Paper Details
Title
Mechanism of central hypopnoea induced by organic phosphorus poisoning
Published Date
Sep 28, 2020
Journal
Volume
10
Issue
1
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