Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
Abstract
Non-invasively probing metabolites within single live cells is highly desired but challenging. Here we utilize Raman spectro-microscopy for spatial mapping of metabolites within single cells, with the specific goal of identifying druggable metabolic susceptibilities from a series of patient-derived melanoma cell lines. Each cell line represents a different characteristic level of cancer cell de-differentiation. First, with Raman spectroscopy,...
Paper Details
Title
Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
Published Date
Sep 24, 2020
Journal
Volume
11
Issue
1
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