Mapping the 17q12–21.1 Locus for Variants Associated with Early-Onset Asthma in African Americans

Volume: 203, Issue: 4, Pages: 424 - 436
Published: Feb 15, 2021
Abstract
Rationale: The 17q12-21.1 locus is one of the most highly replicated genetic associations with asthma. Individuals of African descent have lower linkage disequilibrium in this region, which could facilitate identifying causal variants.Objectives: To identify functional variants at 17q12-21.1 associated with early-onset asthma among African American individuals.Methods: We evaluated African American participants from SAPPHIRE (Study of Asthma...
Paper Details
Title
Mapping the 17q12–21.1 Locus for Variants Associated with Early-Onset Asthma in African Americans
Published Date
Feb 15, 2021
Volume
203
Issue
4
Pages
424 - 436
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