CHD7 Regulates Osteogenic Differentiation of Human Dental Follicle Cells via PTH1R Signaling
Abstract
Chromodomain helicase DNA-binding protein 7 (CHD7) is an ATP-dependent chromatin remodeling enzyme, functioning as chromatin reader to conduct epigenetic modification. Its effect on osteogenic differentiation of human dental follicle cells (hDFCs) remains unclear. Here, we show the CHD7 expression increases with osteogenic differentiation. The knockdown of CHD7 impairs the osteogenic ability of hDFCs, characterized by reduced alkaline...
Paper Details
Title
CHD7 Regulates Osteogenic Differentiation of Human Dental Follicle Cells via PTH1R Signaling
Published Date
Sep 21, 2020
Journal
Volume
2020
Pages
1 - 10
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