Elastin-like polypeptide modified silk fibroin porous scaffold promotes osteochondral repair
Abstract
Silk fibroin (SF) is considered biocompatible and biodegradable for osteochondral repair. However, it lacks a bioactive domain for cell adhesion, proliferation and differentiation, limiting its therapeutic efficacy. To revamp SF as a biomimicking and bioactive microenvironment to regulate cell behaviours, we engineered an elastin-like polypeptide (ELP, Val-Pro-Gly-Xaa-Gly) to modify SF fibers via simple and green dehydrothermal (DHT) treatment....
Paper Details
Title
Elastin-like polypeptide modified silk fibroin porous scaffold promotes osteochondral repair
Published Date
Mar 1, 2021
Journal
Volume
6
Issue
3
Pages
589 - 601
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