Decellularized dermal matrix-based photo-crosslinking hydrogels as a platform for delivery of adipose derived stem cells to accelerate cutaneous wound healing

The development of an effective delivery vehicle that gives rise to a microenvironment that promotes skin regeneration remains a challenge in the field of stem cell-based therapeutic strategy for skin tissue engineering. Here, we fabricated a photo-crosslinkable hydrogel based on a decellularized dermal matrix (DDM) combined with o-nitrobenzene-modified hyaluronic acid (HA-NB). The HA-NB/DDM hydrogels can be crosslinked in situ under UV...