Latest Advances for the Sleeping Beauty Transposon System: 23 Years of Insomnia but Prettier than Ever
Abstract
The Sleeping Beauty transposon system is a nonviral DNA transfer tool capable of efficiently mediating transposition-based, stable integration of DNA sequences of choice into eukaryotic genomes. Continuous refinements of the system, including the emergence of hyperactive transposase mutants and novel approaches in vectorology, greatly improve upon transposition efficiency rivaling viral-vector-based methods for stable gene insertion. Current...
Paper Details
Title
Latest Advances for the Sleeping Beauty Transposon System: 23 Years of Insomnia but Prettier than Ever
Published Date
Sep 16, 2020
Journal
Volume
42
Issue
11
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Notes
History