The effects of size and shape of the ovarian cancer spheroids on the drug resistance and migration
Abstract
Background High fatality in ovarian cancer is attributed to metastasis, propagated by the release of multi-cellular aggregates/spheroids into the peritoneal cavity and their subsequent mesothelial invasion of peritoneal organs. Spheroids are therefore a common and clinically relevant in vitro model for ovarian cancer research. Spheroids in patients vary significantly in size and shape and display enhanced resistance to anti-cancer drugs compared...
Paper Details
Title
The effects of size and shape of the ovarian cancer spheroids on the drug resistance and migration
Published Date
Nov 1, 2020
Journal
Volume
159
Issue
2
Pages
563 - 572
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Notes
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