Methylated DNA Markers of Esophageal Squamous Cancer and Dysplasia: An International Study

Discovery of methylated DNA markers (MDM) of esophageal squamous cell carcinoma (ESCC) has sparked interest in assessing these markers in tissue. We evaluated MDMs in ESCC from three geographically and ethnically distinct populations, and explored the feasibility of assaying MDMs from DNA obtained by swallowed balloon devices.MDMs were assayed in ESCC and normal tissues obtained from the populations of United States, Iran, and China, and from...