Comparative Pharmacokinetic Studies of Paeoniflorin, Albiflorin and Oxypaeoniflorin Between Normal and Cerebral Ischemia–Reperfusion Rats Based on the Simultaneous Determinations Using an UPLC-MS–MS Method

Volume: 83, Issue: 11, Pages: 1345 - 1354
Published: Nov 1, 2020
Abstract
To explore the pharmacokinetic characteristics of the three monoterpene glycosides (paeoniflorin, albiflorin and oxypaeoniflorin) extracted from the Radix Paeoniae Rubra (RPR), we determined the plasma concentrations of these components in the cerebral ischemia–reperfusion (CIR) rats and the normal rats by a self-developed and validated ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS–MS) method. In this study, the CIR...
Paper Details
Title
Comparative Pharmacokinetic Studies of Paeoniflorin, Albiflorin and Oxypaeoniflorin Between Normal and Cerebral Ischemia–Reperfusion Rats Based on the Simultaneous Determinations Using an UPLC-MS–MS Method
Published Date
Nov 1, 2020
Volume
83
Issue
11
Pages
1345 - 1354
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