Cellular Senescence as the Pathogenic Hub of Diabetes-Related Wound Chronicity

Diabetes is the only non-communicable disease with pandemic magnitude. Essentially defined as an endocrine-metabolic condition, its entangled pathophysiology and the broad spectrum of its ever progressing complications has turned this disease an intense investigational target that bridges to cancer, neurodegenerative processes, and ultimately to aging. Diabetic environment contains major stressors for the onset of premature cellular senescence...