Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences

Volume: 16, Issue: 9, Pages: e1009019 - e1009019
Published: Sep 11, 2020
Abstract
Loci identified in genome-wide association studies (GWAS) can include multiple distinct association signals. We sought to identify the molecular basis of multiple association signals for adiponectin, a hormone involved in glucose regulation secreted almost exclusively from adipose tissue, identified in the Metabolic Syndrome in Men (METSIM) study. With GWAS data for 9,262 men, four loci were significantly associated with adiponectin: ADIPOQ,...
Paper Details
Title
Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences
Published Date
Sep 11, 2020
Volume
16
Issue
9
Pages
e1009019 - e1009019
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