Hedgehog Signaling in Skeletal Development: Roles of Indian Hedgehog and the Mode of Its Action.
Volume: 21, Issue: 18, Pages: 6665
Published: Sep 11, 2020
Abstract
Hedgehog (Hh) signaling is highly conserved among species and plays indispensable roles in various developmental processes. There are three Hh members in mammals; one of them, Indian hedgehog (Ihh), is expressed in prehypertrophic and hypertrophic chondrocytes during endochondral ossification. Based on mouse genetic studies, three major functions of Ihh have been proposed: (1) Regulation of chondrocyte differentiation via a negative feedback...
Paper Details
Title
Hedgehog Signaling in Skeletal Development: Roles of Indian Hedgehog and the Mode of Its Action.
Published Date
Sep 11, 2020
Volume
21
Issue
18
Pages
6665
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