Antibody–Drug Conjugates: The Last Decade
Abstract
An armed antibody (antibody–drug conjugate or ADC) is a vectorized chemotherapy, which results from the grafting of a cytotoxic agent onto a monoclonal antibody via a judiciously constructed spacer arm. ADCs have made considerable progress in 10 years. While in 2009 only gemtuzumab ozogamicin (Mylotarg®) was used clinically, in 2020, 9 Food and Drug Administration (FDA)-approved ADCs are available, and more than 80 others are in active clinical...
Paper Details
Title
Antibody–Drug Conjugates: The Last Decade
Published Date
Sep 14, 2020
Journal
Volume
13
Issue
9
Pages
245 - 245
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