Gene Expression Profiling Identifies Akt as a Target for Radiosensitization in Gastric Cancer Cells

Despite the important role of radiotherapy in cancer treatment, a subset of patients responds poorly to treatment majorly due to radioresistance. Particularly the role of radiotherapy has not been established in gastric cancer (GC). Herein, we aimed to identify a radiosensitivity gene signature and to discover relevant targets to enhance radiosensitivity in GC cells.An oligonucleotide microarray (containing 22,740 probes) was performed in 12 GC...