UnaG as a reporter in adeno‐associated virus ‐mediated gene transfer for biomedical imaging
Abstract
Adeno‐associated virus (AAV) is one of the most common gene transfer vectors, but it has a limited capacity. A smaller fluorescent protein is urgently needed since it is more suitable to act as a reporter in AAV. In this study, a bilirubin‐dependent reporter smaller than EGFP, termed UnaG, was found to have the ability to label the neurons of a mouse brain as clearly as EGFP without the addition of exogenous bilirubin. We also found that UnaG's...
Paper Details
Title
Published Date
Sep 15, 2020
Journal
Volume
13
Issue
12
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