Enhancement of biomolecules solubility in aqueous media using designer solvents as additives: An experimental and COSMO-based models' approach

The knowledge about the solubility behavior of different biomolecules can be of interest to the pharmaceutical, chemical, and food industries. In this work, the designer solvents were evaluated as additives to aqueous media to enhance the solubility of hydrophobic biomolecules, namely: quercetin, curcumin, and gallic acid. The solubilities of these biomolecules were explored in terms of experimental data and COSMO-based models' prediction...