Melatonin overcomes MCR-mediated colistin resistance in Gram-negative pathogens
Abstract
Background: Emergence, prevalence and widely spread of plasmid-mediated colistin resistance in Enterobacteriaceae strongly impairs the clinical efficacy of colistin against life-threatening bacterial infections. Combinations of antibiotics and FDA-approved non-antibiotic agents represent a promising means to address the widespread emergence of antibiotic-resistant pathogens. Methods: Herein, we investigated the synergistic activity between...
Paper Details
Title
Melatonin overcomes MCR-mediated colistin resistance in Gram-negative pathogens
Published Date
Jan 1, 2020
Journal
Volume
10
Issue
23
Pages
10697 - 10711
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