A combination of hydrogen bonding and chemical covalent crosslinking to fabricate a novel swim-bladder-derived dry heart valve material yields advantageous mechanical and biological properties.

Published on Feb 13, 2021in Biomedical Materials3.174
· DOI :10.1088/1748-605X/ABB616
Xiaorong Lan5
Estimated H-index: 5
(Sichuan University),
Lan Xiaorong + 2 AuthorsYunbing Wang15
Estimated H-index: 15
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ABSTRACTObjectives: This paper aimed to develop a novel dura mater substitute made from swim bladders.Methods: The swim bladders were decellularized by diverse methods. The physical structure, residual DNA amount, mechanical properties and hemolysis rate were tested. The in vitro mouse embryonic fibroblast cells (MEFs) co-culture and in vivo dural repair surgery were performed to evaluate the biocompatibility of acellular swim bladder (ASBs).Results: The characteristics of different ASBs were ev...
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