Hypoxia-Responsive Polymeric Micelles for Enhancing Cancer Treatment

Polymer drug vectors have shown great potentials in tumor therapy. However, intelligently controlled release of drug has become a major challenge in nanomedicine research. Hypoxia-responsive polymer micelles have received widespread attention in recent years due to the inherent hypoxic state of tumor tissue. In this study, a novel diblock polymer consisting of polyethylene glycol and poly(glutamic acid (3-(2-nitro-imidazolyl)-propyl)) was...