Neonatal Fc receptor in human immunity: Function and role in therapeutic intervention
Volume: 146, Issue: 3, Pages: 467 - 478
Published: Sep 1, 2020
Abstract
The humoral immune response provides specific, long-lived protection against invading pathogens, via immunoglobulin production and other memory functions. IgG, the most abundant immunoglobulin isotype, has the longest half-life and protects against bacterial and viral infections. The neonatal Fc receptor (FcRn) transports IgG across barriers, for example, the placenta, enhancing fetal humoral immunity to levels similar to their mothers’....
Paper Details
Title
Neonatal Fc receptor in human immunity: Function and role in therapeutic intervention
Published Date
Sep 1, 2020
Volume
146
Issue
3
Pages
467 - 478
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