Der p 38 is a bidirectional regulator of eosinophils and neutrophils in allergy

Published: Sep 3, 2020
Abstract
Background: The house dust mite (HDM) is the most common cause of allergic diseases, and TLR4 acts as an overarching receptor for allergic responses. This study aimed to identify novel allergen binding to TLR4 in HDMs and unveil its unique role in allergic responses. Methods: Der p 38 was purified and characterized by LC-MS/MS-based peptide mapping. Biolayer interferometry and structure modeling unveiled TLR4-binding activity and the structure...
Paper Details
Title
Der p 38 is a bidirectional regulator of eosinophils and neutrophils in allergy
Published Date
Sep 3, 2020
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