A Triterpene Lactone from Callistemon citrinus Inhibits the PANC‐1 Human Pancreatic Cancer Cells Viability through Suppression of Unfolded Protein Response
Abstract
Human pancreatic tumor cells such as PANC‐1 are known for their ability to tolerate nutrient starvation and thrive under the hypovascular tumor microenvironment, a phenomenon termed as ‘austerity’. A search of agents that preferentially inhibit the cancer cell viability under the starvation condition without toxicity in the nutrient‐rich condition is a promising approach in anticancer drug discovery. In this study, a triterpene lactone, 3 β...
Paper Details
Title
A Triterpene Lactone from Callistemon citrinus Inhibits the PANC‐1 Human Pancreatic Cancer Cells Viability through Suppression of Unfolded Protein Response
Published Date
Sep 30, 2020
Journal
Volume
17
Issue
10
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