Brain metastasis from hepatic cholangiolocellular carcinoma in a young female without chronic liver disease

A 31-year-old female was hospitalized due to severe headache, dizziness and nausea. She had been diagnosed with hepatic cholangiolocellular carcinoma (CLC; Fig. 1A) without chronic liver disease 15 months earlier and had received chemotherapy. Brain magnetic resonance imaging showed a 5-cm mass with intratumoral hemorrhage in the left frontal cortex (Fig. 1B and C). To ameliorate symptoms, surgical resection of the tumor was performed under...