Abstract 2449: A novel function of FTO in ovarian cancer stem cells through m6A RNA demethylation
Abstract
Introduction: N6-Methyladenosine (m6A) is the most abundant internal modification in mammalian messenger RNAs (mRNAs). Although previous studies have showed that RNA methylation is reversible and plays important roles in various cellular processes, such as metabolism, stem cell development, and self-renewal, its functions in cancer remain elusive. The fat mass- and obesity-associated protein (FTO) is an m6A demethylase and was described as an...
Paper Details
Title
Abstract 2449: A novel function of FTO in ovarian cancer stem cells through m6A RNA demethylation
Published Date
Aug 15, 2020
Journal
Volume
80
Pages
2449 - 2449
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