NLRP3 played a role in Trichinella spiralis-triggered Th2 and regulatory T cells response
Abstract
Trichinella spiralis maintains chronic infections within its host. Muscle larvae excretory-secretory products (MLES) typically induce parasite-specific immune responses such as the Th2 response and regulatory T cells (Tregs) by modulating dendritic cell (DC) phenotype via the recognition of pattern recognition receptors (PRRs), such as Nod-like receptors (NLRs). We aimed to investigate the role of NLRP3 in T. spiralis -triggered immune response....
Paper Details
Title
NLRP3 played a role in Trichinella spiralis-triggered Th2 and regulatory T cells response
Published Date
Aug 27, 2020
Journal
Volume
51
Issue
1
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