Beyond structural models for the mode of action: How natural antimicrobial peptides affect lipid transport
Abstract
Hypothesis: Most textbook models for antimicrobial peptides (AMP) mode of action are focused on structural effects and pore formation in lipid membranes, while these deformations have been shown to require high concentrations of peptide bound to the membrane. Even insertion of low amounts of peptides in the membrane is hypothesized to affect the transmembrane transport of lipids, which may play a key role in the peptide effect on membranes....
Paper Details
Title
Beyond structural models for the mode of action: How natural antimicrobial peptides affect lipid transport
Published Date
Jan 1, 2021
Volume
582
Pages
793 - 802
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