Multiorgan Metabolomics and Lipidomics Provide New Insights Into Fat Infiltration in the Liver, Muscle Wasting, and Liver–Muscle Crosstalk Following Burn Injury

Volume: 42, Issue: 2, Pages: 269 - 287
Published: Sep 2, 2020
Abstract
Burn injury mediated hypermetabolic syndrome leads to increased mortality among severe burn victims, due to liver failure and muscle wasting. Metabolic changes may persist up to 2 years following the injury. Thus, understanding the underlying mechanisms of the pathology is crucially important to develop appropriate therapeutic approaches. We present detailed metabolomic and lipidomic analyses of the liver and muscle tissues in a rat model with a...
Paper Details
Title
Multiorgan Metabolomics and Lipidomics Provide New Insights Into Fat Infiltration in the Liver, Muscle Wasting, and Liver–Muscle Crosstalk Following Burn Injury
Published Date
Sep 2, 2020
Volume
42
Issue
2
Pages
269 - 287
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