New approaches for targeting platinum-resistant ovarian cancer
Abstract
Platinum is the backbone of systemic treatment in ovarian cancer and development of platinum resistance is associated with poor survival. Here, we perform a comprehensive review of the literature regarding resistance mechanisms and advances in therapy for platinum resistant ovarian cancer, with a focus on high-grade serous carcinoma. Platinum resistance can be intrinsic or acquired. Resistance mechanisms are complex and diverse. Intracellular...
Paper Details
Title
New approaches for targeting platinum-resistant ovarian cancer
Published Date
Dec 1, 2021
Journal
Volume
77
Pages
167 - 181
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