Systemic inflammation as a moderator between sleep and incident dementia

To determine whether C-reactive protein (CRP), a marker of systemic inflammation, moderates the association between sleep and incident dementia.We studied Framingham Heart Study participants who completed at baseline a serum CRP assessment and in-home polysomnography to measure sleep duration, sleep efficiency, sleep latency, wake after sleep onset (WASO), number of awakenings, arousal index, and apnea-hypopnea index. Participants were divided...