Investigating the impact of open label design on patient‐reported outcome results in prostate cancer randomized controlled trials
Abstract
Background While open‐label randomized controlled trials (RCT) are common in oncology, some concerns have been expressed with regard to Patient‐Reported Outcomes (PRO)‐based claims stemming from these studies. We aimed to investigate the impact of open‐label design in the context of prostate cancer (PCa) RCTs with PRO data. Methods Randomized controlled trials of PCa with a PRO endpoint published between 2004 and 2018 were considered. RCTs were...
Paper Details
Title
Investigating the impact of open label design on patient‐reported outcome results in prostate cancer randomized controlled trials
Published Date
Aug 26, 2020
Journal
Volume
9
Issue
20
Pages
7363 - 7374
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